Recombinant human erythropoietin을 이용한 무수혈 구강암절제 및 재건
Oral cancer resection and reconstruction without blood transfusion by using recombinant human erythropoietin
김철환, 이충현,
소속 상세정보
김철환 ( Kim Cheol-Whan ) - 단국대학교 치과대학 구강악안면외과학교실
이충현 ( Lee Chung-Hyun ) - 단국대학교 치과대학 구강악안면외과학교실
KMID : 0355620110370010009
Abstract
Recently, the population of patients who refuse transfusion has increased for both religious and non-religious reasons, even in life threatening emergency situations. Their refusal has highlighted the need to develop nonblood transfusion surgery techniques to decrease the risk from blood transfusions.
A 57-year woman with an ulcerative lesion on the gingiva of the right upper molar area visited the department of oral and maxillofacial surgery in Dankook University Dental Hospital. After a preliminary evaluation, the patient was diagnosed with squamous cell carcinoma. As she refused blood transfusion during surgery for religious reasons, surgery was planned using recombinant human erythropoietin (rHuEPO) without a blood transfusion. The patient underwent a partial maxillectomy, supraomohyoid neck dissection, free radial forearm flap and split thickness skin graft under general anesthesia. rHuEPO and iron were used before and after surgery. The hemoglobin/hematocrit (Hb/Hct) level, iron (Fe) and total iron-binding capacity (TIBC) were assessed. The patient recovered completely without any blood transfusions. rHuEPO is a viable alternative for patients with religious objections to receiving blood transfusions.
키워드
Recombinant erythropoietin; Blood transfusion; Mouth neoplasms
원문 및 링크아웃 정보
등재저널 정보